Is there any way to tuning
AutoPager performance?
Yes. We are continue improving the performance. And we are currently focus on performance. A performance improved version is expected soon.
But you can try this tip if you don't have a fast pc. It can reduce the memory used and make it fast to get the matched setting for a sit.
AutoPager includes some site configuration repository to get the site settings. You can disable some them if you don't need site settings in that repository. Please don't disable autopager.xml and we are not suggest to disable autopagerTee.xml. autopager.xml is your local repository. autopagerTee.xml is the AutoPager offical main repository. You can do it by goto Tools->Auto Pager->Manage Setting, select the repository in the list and uncheck the Enabled in the right side of the window. Click apply or OK to make it take effect. Like this:

If disable some repository still not work, you can disable all the repository other then autopager.xml. Then follow this way to clone the necessary setting for the site your want to auto paging:
Open the page, goto the page you want to auto paging, open AutoPager setting dialog by Tools->Auto Pager->Manage Setting. The site setting for the current browsing page will be selected. You can click Clone or Clone to Edit to copy it to your local repository. Click apply or OK to apply it.